Last Updated: 1 April 2025
Ohio-based orthodontic solutions provider Orthobrain® has announced a fresh injection of $7.5 million in growth capital. CareCapital, one of the largest investors in the dental care industry, led the funding, with JumpStart Ventures and JobsOhio also joining as key participants.
This latest capital comes on the heels of remarkable momentum: the company’s revenue climbed by 145% year-over-year, while doctor registrations grew by over 185% in the same period.
Orthobrain attributes these gains to a unique approach that makes orthodontic services more accessible for general dental practices.
"At orthobrain, we are not just transforming orthodontic care, we are giving general practitioners the confidence, tools and education to seamlessly integrate orthodontics into their practices. This funding is a testament to the success of our model and the trust we've built with both our investors and partners. It will drive continued innovation, ensuring more dentists worldwide have access to the support they need to grow their practices and provide outstanding patient care."
Richard Uria, President of Orthobrain®
Industry observers note a rising trend of general dentists seeking in-house orthodontic services, allowing them to retain more patients and deliver a broader scope of care.
Orthobrain stands at the forefront of this shift, offering a system that supports doctors through an integrated platform and clinical guidance.
"Our customers are experiencing tangible business growth after implementing Orthobrain solutions. The ability to offer orthodontic services in-house has not only increased practice profitability but has also strengthened patient retention and satisfaction."
Julie Radzyminski, VP of Consumable Merchandising and Product Development at Benco Dental
The new funds will help Orthobrain hire additional team members, enhance its technology platform, and expand global marketing efforts. Central to its strategic roadmap is the development of advanced solutions designed to streamline clinical workflows and support higher patient volumes.
Educational initiatives will also receive dedicated resources, allowing more practitioners to build skills and confidence in providing orthodontic treatments.
“At orthobrain, we are revolutionizing the way orthodontic care is delivered by enabling general practitioners to integrate orthodontics with ease and confidence. This new capital allows us to build on our strong foundation, accelerate our technology roadmap, and continue to empower doctors worldwide to transform smiles and lives.”
Dr. Dan German, Founder, CEO, and Chief Orthodontist of Orthobrain®
Beyond technology, Orthobrain plans to strengthen its training ecosystem through Orthobrain University, an on-demand learning platform offering courses, mentorship, and specialized support.
The company’s proprietary SimplyClear™ Aligners—designed to help general dentists provide aligner treatment with built-in orthodontic guidance—will also be extended to more regions and practitioners.
Founded in 2016 by Dr. Dan German, Orthobrain set out to simplify orthodontic care by combining expert mentorship with user-friendly digital tools. Headquartered in Cleveland, the company has since developed a suite of services that bridge the gap between orthodontic specialists and general practices. By taking on everything from initial patient evaluation to case completion, Orthobrain reduces the barriers that often keep dental teams from offering orthodontic services.
In 2022, Orthobrain introduced SimplyClear™, a clear aligner system built with the everyday dentist in mind. This addition, along with the company’s total-service model, helped propel significant revenue and user growth.
Orthobrain continues to refine its offerings, aiming to give general dental practices anywhere in the world easy access to high-quality orthodontic expertise.
“Orthobrain exemplifies Ohio's leadership in healthcare innovation. Their breakthrough platform is revolutionizing dental care delivery while establishing Ohio as a hub for advanced healthcare solutions.”
J.P. Nauseef, President and CEO of JobsOhio
The $7.5 million in growth capital is led by CareCapital—one of the largest investors in the dental care industry—and JumpStart Ventures, with additional support from JobsOhio, underscoring strong confidence in orthobrain’s vision and continued expansion.
"Orthobrain stands at the intersection of clinical excellence and technological innovation. By seamlessly integrating specialist expertise with comprehensive support tools, they're enabling general dentists to confidently expand into orthodontics. We're excited to fuel their continued growth as they enhance access to high-quality orthodontic care."
Hardik Desai, Managing Partner at JumpStart Ventures
